Spherical carrier (Celldex1)

Agarose beads are used as the matrix, the surface is covered with positively charged DEAE groups, the density is 1.045g/ml, the dry weight diameter is 50-100, the diameter after hydration is 145-240, the expansion coefficient is 17 ~ 22ml / g, the number of microcarriers per gram of dry weight is about 4.3x106, and the cell adhesion area is 4400cm2 / g (dry weight)

Applications:

• For Bioreactors
• Adherent cells
• Suspension culture

A spherical bioreactor carrier refers to a microcarrier that has a spherical shape and is utilized in various biotechnological applications. It is created by bonding diethylamino chloroethane onto agarose microspheres, which facilitates the attachment of cells to the carrier surface. Due to its effectiveness, it has become the most commonly employed microcarrier for adherent cell suspension culture.

This type of carrier plays a crucial role in the research, development, and production of biological products. It provides a favorable environment for the cultivation of cells and facilitates their growth and proliferation. The spherical shape of the carrier allows for efficient mixing and uniform distribution of nutrients and gases throughout the culture medium.

By using a spherical bioreactor carrier, researchers and biotechnologists can enhance the productivity and yield of their cell cultures. The cells easily attach to the carrier, promoting cell-cell interactions and the formation of three-dimensional structures, which can mimic the natural tissue environment more accurately. This characteristic is particularly valuable in tissue engineering and regenerative medicine applications.

The spherical bioreactor carrier is scalable, enabling the generation of large quantities of cells or biological products. The spherical bioreactor carrier is designed to offer several advantages over traditional flake bioreactor carriers. This makes it a preferred choice in pharmaceutical research and development, where the production of therapeutic proteins, vaccines, and other biological molecules is essential.